ESM1 promote proliferation, invasion and angiogenesis via Akt/mTOR and Ras pathway in kidney renal clear cell carcinoma

Abstract The most common types of renal carcinoma is kidney renal clear cell carcinoma (KIRC).ESM1 is a secreted protein, which involved in, lipids and glucose metabolism, but their role in angiogenesis is contradictory in different disease, especially in KIRC.Bioinformatic analysis confirmed the ESM1 expression and prognosis in KIRC.IHC staining r

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A Survey of Universal Quantum von Neumann Architecture

The existence of universal quantum computers has been theoretically well established.However, building up a real quantum computer system ULTRA DEFINING GEL not only relies on the theory of universality, but also needs methods to satisfy requirements on other features, such as programmability, modularity, scalability, etc.To this end, here we study

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The atmospheric background situation in northern Scandinavia during January/February 2003 in the context of the MaCWAVE campaign

The atmosphere background wind field controls the propagation of gravity waves from the troposphere through the stratosphere into the mesosphere.During January 2003 the MaCWAVE campaign took place at Esrange, with the purpose of observing vertically ascending waves induced by orography.Temperature data from the U. Bonn lidar at Esrange (68°

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